Validating aurora b as an anticancer drug target dating for widows and widowers
]; molecular factors capable of predicting clinical outcome of HCC and acting as potential therapeutic targets remain limited.
After resection, tumor tissues were immediately cut into small pieces, snap frozen in liquid nitrogen, and stored in deep freezer.
Patients had received comprehensive pathologic assessment and regular follow-up at National Taiwan University Hospital, as described previously .
Therefore, determination of the distinctive roles in carcinogenesis and individual clinical significance of Aurora A and Aurora B is mandatory.
The aims of this study were to elucidate the clinicopathologic significance of During the period January 1987 through December 1997, 160 surgically resected, primary unifocal HCCs were selected for this study.
Genomic instability has been correlated with hepatocarcinogenesis .
These findings indicated that Aurora kinases may be important biomarkers and potential therapeutic targets in HCC.