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According to Deadline.com, Gandolfini's HBO-based Attaboy Prods.
had the actor-producer set to costar with Steve Carell in Bone Wars, about a pair of real-life paleontologists after the Civil War who discovered the fossils of more than 160 dinosaurs.
The actor was taken to Policlinico Umberto I at 10.20pm, and was pronounced dead at 11pm when efforts to revive him proved unsuccessful, according to Dr Claudio Modini, head of the hospital's emergency room.
Gandolfini's managers Mark Armstrong and Nancy Sanders paid tribute to the star, saying in a statement: 'Our hearts are shattered and we will miss him deeply.
', tweeted Christina Applegate, his co-star in the 2004 comedy Surviving Christmas. I’m in shock.' Following the success of the HBO television series - which finished in 2007 - he continued to make big screen appearances in critically acclaimed films including In The Loop and The Taking of Pelham 123.'I am so deeply saddened by the untimely passing of sweet James Gandolfini!
In a sign that he was generous until the end, a holidaymaker claimed on Facebook that Gandolfini, who was staying at the same hotel, witnessed a boy stealing a few Euros from her and 'ran after me in to the elevator to make sure that I was ok.' 'Good man,' she added.
He said that the greatest tragedy was that Gandolfini's son and daughter would grow up without their father.
But according to the ex-wife of talented and kindly James Gandolfini, the complicated personality that made Tony Soprano the TV icon of the last decade fought a battle with drug addiction, alcohol and inner demons that would cause him to lash out at himself violently.
The actor said that Gandolfini was a generous guy with no airs about him who made everyone feel comfortable.
He told of a time that Gandolfini had been scheduled to make an appearance at his Brooklyn restaurant and despite being ill and it pouring with rain, he took pictures with everyone in a line of people who had queued around the block.